Sermorelin Reconstitution Calculator & Dosage Chart
In short: mix a 5 mg vial of Sermorelin with 2 ml of bacteriostatic water. That gives 2.50 mg/ml, so a typical 300 mcg dose is 12 units on a U-100 insulin syringe — about 16 doses per vial. Reported protocols range 200 mcg–500 mcg, nightly before bed.
Sermorelin is the first 29 amino acids of natural GHRH — the oldest and most clinically familiar GH-releasing peptide, widely prescribed in anti-aging and wellness clinics as a nightly injection. Full overview: what is Sermorelin? →
Calculate your exact dose
Typical range: 200 mcg–500 mcg, nightly before bed
Sermorelin mixing chart — 5 mg vial
Units to draw for a 300 mcg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 300 mcg dose = | Per unit |
|---|---|---|---|
| 1 ml | 5.00 mg/ml | 6.0 units | 50.0 mcg |
| 2 ml ← typical | 2.50 mg/ml | 12 units | 25.0 mcg |
| 2.5 ml | 2.00 mg/ml | 15 units | 20.0 mcg |
| 3 ml | 1.67 mg/ml | 18 units | 16.7 mcg |
| 5 ml | 1.00 mg/ml | 30 units | 10.0 mcg |
Sermorelin reconstitution by vial size — 2 mg / 5 mg / 10 mg
How much water for each vial size, and what a 300 mcg dose becomes in syringe units. Bigger vials hold more doses; they do not change the dose.
| Vial | Water | Concentration | 300 mcg dose = | Doses per vial |
|---|---|---|---|---|
| 2 mg | 1 ml | 2.00 mg/ml | 15 units | 6 |
| 2 mg | 2 ml | 1.00 mg/ml | 30 units | 6 |
| 2 mg | 3 ml | 0.67 mg/ml | 45 units | 6 |
| 5 mg | 1 ml | 5.00 mg/ml | 6.0 units | 16 |
| 5 mg | 2 ml | 2.50 mg/ml | 12 units | 16 |
| 5 mg | 3 ml | 1.67 mg/ml | 18 units | 16 |
| 10 mg | 1 ml | 10.00 mg/ml | 3.0 units | 33 |
| 10 mg | 2 ml | 5.00 mg/ml | 6.0 units | 33 |
| 10 mg | 3 ml | 3.33 mg/ml | 9.0 units | 33 |
Protocol reference
FAQ
How much bacteriostatic water do you add to Sermorelin?+
Most protocols mix a 5 mg vial of Sermorelin with 2 ml of bacteriostatic water. This gives 2.50 mg/ml, so a typical 300 mcg dose is 12 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical Sermorelin dose?+
Commonly reported Sermorelin protocols use 200 mcg to 500 mcg, nightly before bed, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 5 mg vial of Sermorelin?+
At 300 mcg per dose, a 5 mg vial contains about 16 doses, regardless of how much water you add.
How should Sermorelin be stored?+
Reconstituted: refrigerate, typically used within 4 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. Sermorelin may not be approved for human use in your jurisdiction.